This open access book collects the historical and medial perspectives of a systematic and epistemological analysis of the complicated, multifaceted relationship between model and mathematics, ranging from, for example, the physical mathematical models of the 19th century to the simulation and digital modelling of the 21st century. The aim of this anthology is to showcase the status of the mathematical model between abstraction and realization, presentation and representation, what is modeled and what models. This book is open access under a CC BY 4.0 license.