Natural Compounds as Drugs II

Progress in Drug Research 66

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Bibliografische Daten
ISBN/EAN: 9783764385941
Sprache: Englisch
Umfang: x, 428 S., 185 s/w Illustr., 27 farbige Illustr.,
Auflage: 1. Auflage 2008
Einband: gebundenes Buch

Beschreibung

InhaltsangabeActivation of fungal silent gene clusters: A new avenue to drug discovery.- Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin.- Application of natural product-inspired diversity-oriented synthesis to drug discovery.- Cheminformatics analysis of natural products: Lessons from nature inspiring the design of new drugs.- Chemical-genetic approaches for exploring the mode of action of natural products.- Epothilones as lead structures for new anticancer drugs - pharmacology, fermentation, and structure-activity-relationships.- Histone deacetylase inhibitors from microorganisms: the Astellas experience.- Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720.- Artemisinin - an innovative cornerstone for anti-malaria therapy.

Inhalt

Activation of fungal silent gene clusters: An new avenue to drug discovery.- Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin.- Application of natural product-inspired diversity-oriented synthesis to drug discovery.- Cheminformatics analysis of natural products: Lessons from nature inspiring the design of new drugs.- Chemical-genetic approaches for exploring the mode of action of natural products.- Epothilones as lead structures for new anticancer drugs - pharmacology, fermentation, and structure-activity-relationships.- Histone deacetylase inhibitors from microorganisms: the Astellas experience.- Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720.- Artemisinin - an innovative cornerstone for anti-malaria therapy.

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Springer Basel AG in Springer Science + Business Media
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