National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner. This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.

InhaltsangabeGeneral research aspects.- Problems with terminology and definitions.- Etymological background and further clarifying remarks.- Scientific background.- Ethics.- Law.- Key Cases in chimbrids research.- Case 1 – Muotri: Transfer of human embryonic stem cell-derived neurons in mouse bra.- Case 2 – Chen: Interspecies somatic cell nuclear transfer.- Case 3 – Bailey: Animal-Human Xenotransplantation.- Case 4 – Fink: Porcine Xenografts in Parkinson's Disease and Huntington's Disease patients.- Case 5 – McCune: The SCID-hu Mouse.- Case 6 – EMEA: Transgenic goat producing human antithromb.- Case 7 – O’Doherty: Mouse with human chromosome.- Case 8 – Yanagimachi: Hamster egg penetration test.- Case 9 – Fehilly: Human-animal embryo mixing.- Case 10 – Nan et al.: Interspecies gestation.- Short Remarks to the cases 1-10 in the light of European legal order.- Summary, Conclusions and Recommendations.- General remarks.- Scientific overview of human-animal mixtures.- Ethical Aspects.- Legal Aspects.- Recommendations.- Annex A. Chimbrids - Scientific, Ethical and Legal Reports.- Science.- Ethics.- Law.- Annex B. Country Reports on the 10 Cases.- Germany: Case 1-10 according to German Law:.- UK: Case 1-10 according to UK law.- France Legal Issues in French Law: the case studies.- Sweden – Case 1-10 according to Swedish law.- Spain – Case 1-10 according to Spanish law.- Austria – Case 1-10 according to Austrian Law.- Switzerland Case 1 to 10 according to Swiss Law.- USA – Case comments.- Canada.- Israel – Case 1-10 according to Israeli law.- Japan – Case 1-10 according to Japanese Law.

General Research Aspects.- Key Cases in Chimbrids Research.- Summary, Conclusions and Recommendations.