InhaltsangabePart I: Photoreactive Small Molecules for Affecting Biological Function 1. Introduction to Part I: Caged Neurotransmitters            James J. Chambers and Richard H. Kramer 2. Targeting and Excitation of Photoactivatable Molecules: Design Considerations for Neurophysiology Experiments            Eugene F. Civillico, J. Peter Rickgauer, and Samuel S.-H. Wang 3. Are Caged Compounds Still Useful?            Graham C.R. Ellis-Davies 4. Chromophores for the Delivery of Bioactive Molecules with Two-Photon Excitation            Timothy M. Dore and Hunter C. Wilson Part II: Imparting Light Sensitivity on Cells Using Photosensitive Proteins 5. Introduction to Part II: Natural Photosensitive Proteins            James J. Chambers and Richard H. Kramer 6. Light-Activated Ion Pumps and Channels for Temporally-Precise Optical Control of Activity in Genetically-Targeted Neurons            Brian Y. Chow, Xue Han, Jacob G. Bernstein, Patrick E. Monahan, and Edward S. Boyden 7. Vertebrate and Invertebrate Rhodopsins: Light Control of G Protein Signaling            Davina V. Gutierrez, Eugene Oh, and Stefan Herlitze 8. Restoring Visual Function after Photoreceptor Degeneration: Ectopic Expression of Photosensitive Proteins in Retinal Neurons            Bin Lin and Richard H. Masland Part III: Molecular Photoswitch Conjugates to Remotely Affect Activity 9. Introduction to Part III: Small Molecule Photoswitches            James J. Chambers and Richard H. Kramer 10. Photoswitch Design            Andrew A. Beharry and G. Andrew Woolley 11. Photoswitchable Voltage-Gated Ion Channels            Doris L. Fortin and Richard H. Kramer 12. Optical Manipulation of Protein Activity and Protein Interactions Using Caged Proteins and Optical Switch Protein Conjugates            Yuling Yan and Gerard Marriott 13. Structure-Based Design of Light-Controlled Proteins            Harald Janovjak and Ehud Y. Isacoff 14. Photoswitchable Ligand-Gated Ion Channels            Pau Gorostiza and Ehud. Y. Isacoff

Part I: Photoreactive Small Molecules for Affecting Biological Function   1. Introduction to Part I: Caged Neurotransmitters             James J. Chambers and Richard H. Kramer   2. Targeting and Excitation of Photoactivatable Molecules: Design Considerations for Neurophysiology Experiments             Eugene F. Civillico, J. Peter Rickgauer, and Samuel S.-H. Wang   3. Are Caged Compounds Still Useful?             Graham C.R. Ellis-Davies   4. Chromophores for the Delivery of Bioactive Molecules with Two-Photon Excitation             Timothy M. Dore and Hunter C. Wilson   Part II: Imparting Light Sensitivity on Cells Using Photosensitive Proteins   5. Introduction to Part II: Natural Photosensitive Proteins             James J. Chambers and Richard H. Kramer   6. Light-Activated Ion Pumps and Channels for Temporally-Precise Optical Control of Activity in Genetically-Targeted Neurons             Brian Y. Chow, Xue Han, Jacob G. Bernstein, Patrick E. Monahan, and Edward S. Boyden   7. Vertebrate and Invertebrate Rhodopsins: Light Control of G Protein Signaling             Davina V. Gutierrez, Eugene Oh, and Stefan Herlitze   8. Restoring Visual Function after Photoreceptor Degeneration: Ectopic Expression of Photosensitive Proteins in Retinal Neurons             Bin Lin and Richard H. Masland   Part III: Molecular Photoswitch Conjugates to Remotely Affect Activity   9. Introduction to Part III: Small Molecule Photoswitches             James J. Chambers and Richard H. Kramer   10. Photoswitch Design             Andrew A. Beharry and G. Andrew Woolley   11. Photoswitchable Voltage-Gated Ion Channels             Doris L. Fortin and Richard H. Kramer   12. Optical Manipulation of Protein Activity and Protein Interactions Using Caged Proteins and Optical Switch Protein Conjugates             Yuling Yan and Gerard Marriott   13. Structure-Based Design of Light-Controlled Proteins             Harald Janovjak and Ehud Y. Isacoff   14. Photoswitchable Ligand-Gated Ion Channels             Pau Gorostiza and Ehud. Y. Isacoff

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