Molecular and Cellular Therapeutics aims to bring together key developments in the areas of molecular diagnostics, therapeutics and drug discovery. The book covers topics including diagnostics, therapeutics, model systems, clinical trials and drug discovery. The developing approaches to molecular and cellular therapies, diagnostics and drug discovery are presented in the context of the pathologies they are devised to treat.

InhaltsangabeList of contributors Preface 1 Cytochrome P450 pharmacogenetics: from bench to bedside Imtiaz M. Shah, Catherine J. Breslin and Simon P. Mackay 2 Cancer biomarkers for diagnosis, prognosis and therapy Debmalya Barh, Vaishali Agte, Dipali Dhawan, Varsha Agte and Harish Padh 3 HER2 targeted therapy-induced gastrointestinal toxicity: from the clinical experience to possible molecular mechanisms Noor AlDasooqi, Rachel J. Gibson, Joanne M. Bowen and Dorothy M. Keefe 4 Antibodytargeted photodynamic therapy Mahendra Deonarain, Ioanna Stamati and Gokhan Yahioglu 5 Antiageing strategy of the lung for chronic inflammatory respiratory disease targeting protein deacetylases Kazuhiro Ito and Nicolas Mercado 6 RNA interference: from basics to therapeutics Sunit Kumar Singh and Praveensingh B. Hajeri 7 Delivery of RNAi effectors by tkRNAi Hermann Lage, Andrea Kr¨uhn and Johannes H. Fruehauf 8 Human stem cell therapy M. Ian Phillips, Yao-Liang Tang and Henrique Cheng 9 Gene therapy in organ transplantation Thomas Ritter and Matthew D. Griffin 10 Advances in the treatment of Alzheimer's disease Michael S. Rafii 11 Novel molecular therapeutics in Parkinson's disease Susana Gonc¸alves, Hugo Vicente Miranda and Tiago F. Outeiro 12 Emerging insights and therapies for human microbial disease Joanne L. Fothergill and Craig Winstanley 13 Vaccine design and vaccination Niall McMullan Index 305