This handbook is a collection of clinical narratives that underscore the heterogeneous and unpredictable presentation of multiple sclerosis (MS) and give real-world clinical context to recent drug developments. This accessible and concise publication is intended to be used by a wide range of medical professionals, from specialist neurologists to medical trainees with an interest in neurology. An ideal clinical resource,Case Studies in Multiple Sclerosis provides an evidence-based discussion of each case, with an aim to enhance effective diagnosis and treatment of patients with MS and MS-related conditions.

Dr Paul Giacomini is a neurologist with expertise in multiple sclerosis, neuro-inflammatory disorders and advanced neuroimaging techniques. He is an Assistant Professor of Neurology and Neurosurgery at McGill University and an attending physician at the Montreal Neurological Institute. Dr Giacomini serves as the Director of the McGill Neurology Fellowship Program in Multiple Sclerosis and Neuro-Inflammatory Disorders, and as the Associate Director of the MNI Multiple Sclerosis Clinic.

1. Optic Neuritis. - 2. Myelitis.- 3. Disease-Modifying Therapies in MS.- 4. Management of Replaces with Corticosteroids.- 5. Breakthrough Disease.- 6. Progressive Multifocal Leukoencephalopathy.- 7. Induction Therapy.- 8. Diagnosing Primary Progressive Multiple Sclerosis.- 9. Symptomatic Care in Primary Progressive Multiple Sclerosis.- 10. Diagnosing Secondary Progressive Multiple Sclerosis.- 11. Walking Disability in MS.- 12. Cognitive Impairment in MS.- 13. Acute Disseminated Encephalomyelitis.- 14. Pediatric Multiple Sclerosis.- 15. Pediatric Multiple Sclerosis Mimics.- 16. Prenatal Planning with MS.- 17.MS Therapies and Pregnancy.- 18. Postpartum Issues with MS.- 19. Neuromyelitis Optica.