Beschreibung
InhaltsangabeA Brief Introduction to the History of the ß-Amyloid Protein (Aß) of Alzheimer's Disease.- The Aßcentric Pathway of Alzheimer's Disease.- The Function of the Amyloid Precursor Protein Family.- The involvement of Aß in the neuroinflammatory response.- Amyloid ß-Peptide(1-42), Oxidative Stress, and Alzheimer's Disease.- Amyloid Toxicity, Synaptic Dysfunction and the Biochemistry of Neurodegeneration in Alzheimer's Disease.- Aß Variants and Their Impact on Amyloid Formation and Alzheimer's Disease Progression.- Copper Coordination by ß-Amyloid and the Neuropathology of Alzheimer's Disease.- Cholesterol and Alzheimer's Disease.- Amyloid ß peptide and central cholinergic neurons: involvement in normal brain function and Alzheimer's disease pathology.- Physiological and Neurotoxic Properties of Aß Peptides.- Impact of ß-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models.- Glial Cells and Aß Peptides in Alzheimer's Disease Pathogenesis.- The Role of Presenilins in Abeta-Induced Cell Death in Alzheimer's Disease.- Immunotherapeutic approaches to Alzheimer's disease.- Mouse Models of Alzheimer's Disease.
Inhalt
A Brief Introduction to the History of the ß-Amyloid Protein (Aß) of Alzheimer¿s Disease.- The Aßcentric Pathway of Alzheimer¿s Disease.- The Function of the Amyloid Precursor Protein Family.- The involvement of Aß in the neuroinflammatory response.- Amyloid ß-Peptide(1-42), Oxidative Stress, and Alzheimer¿s Disease.- Amyloid Toxicity, Synaptic Dysfunction and the Biochemistry of Neurodegeneration in Alzheimer¿s Disease.- Aß Variants and Their Impact on Amyloid Formation and Alzheimer¿s Disease Progression.- Copper Coordination by ß-Amyloid and the Neuropathology of Alzheimer¿s Disease.- Cholesteroland Alzheimer¿s Disease.- Amyloidß peptide and central cholinergic neurons: involvement in normal brain function and Alzheimer¿s disease pathology.- Physiological and Neurotoxic Properties of Aß Peptides.- Impact of ß-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models.- Glial Cells and Aß Peptides in Alzheimer¿s Disease Pathogenesis.- The Role of Presenilins in Abeta-Induced Cell Death in Alzheimer¿s Disease.- Immunotherapeutic approaches to Alzheimer¿s disease.- Mouse Models of Alzheimer¿s Disease.
