Drug Delivery Systems, Second Edition expands upon the previous edition with current, detailed methods and technologies to further study drug delivery. With new chapters on nanobiotechnology techniques, experimental methods and the clinical use for the intrathecal delivery of analgesics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Drug Delivery Systems, Second Edition will be useful for pharmaceutical scientists as well as well as physicians both in the academic institutions and in the industry.

Inhaltsangabe1. Current Status and Future Prospects of Drug Delivery Systems K. K. Jain 2. A Method for Screening Mitochondrial Fusogenic Envelopes for use in Mitochondrial Drug DeliveryYuma Yamada and Hideyoshi Harashima 3. Ultrasound-directed, Site-specific Gene DeliveryJason Castle    and   Steven B. Feinstein 4. Synthesis of Thermoresponsive Polymers for Drug DeliverySushil Mishra, Arnab De, and Subho Mozumdar 5. Recombinant Stem Cells as Carriers for Cancer Gene TherapyYu-Lan Hu and  Jian-Qing Gao 6. Microfluidic-based Manufacture of siRNA-lipid Nanoparticles for Therapeutic ApplicationsColin Walsh, Kevin Ou, Nathan M. Belliveau, Tim J. Leaver, Andre W. Wild, Jens Huft, Paulo J. Lin, Sam Chen, Alex K. Leung, Justin B. Lee, Carl L. Hansen, Robert J. Taylor, Euan C. Ramsay, Pieter R. Cullis 7. Microneedle-iontophoresis Combinations for Enhanced Transdermal Drug DeliveryRyan F. Donnelly, Martin J. Garland, and Ahlam Zaid Alkilani  8. Polymer Nanoparticle-based Controlled Pulmonary Drug DeliveryMoritz Beck-Broichsitter, Alexandra C. Dalla-Bona, Thomas Kissel, Werner Seeger, and Thomas Schmehl 9. Antibody Labeling with Radioiodine and Radiometals Suprit Gupta, Surinder Batra, and Maneesh Jain 10. Self Assembling Peptide -based Delivery of Therapeutics for Myocardial InfarctionArchana V. Boopathy and Michael E. Davis 11. Applications of Chitosan Nanoparticles in Drug DeliveryH. A. Tajmir-Riahi, Sh. Nafisi,  S. Sanyakamdhorn, D. Agudelo and P. Chanphai 12. A Method for Evaluating Nanoparticle Transport through the Blood Brain Barrier in vitroDaniela Guarnieri, Ornella Muscetti and Paolo A. Netti  13. Bacterial Systems for Gene Delivery to Systemic TumoursJoanne Cummins, Michelle Cronin, Jan Peter van Pijkeren, Cormac G.M. Gahan and Mark Tangney 14. Synthesis of a Smart Nanovehicle for Targeting Liver Arnab De, Sushil Mishra, Seema Garg, and Subho Mozumdar15. Intranasal Delivery of Chitosan-siRNA Nanoparticle Formulation to the BrainMeenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha, and Satya Prakash 16. Intrathecal Delivery of AnalgesicsJose De Andres, Juan Marcos Asensio-Samper, and  Gustavo Fabregat-Cid