InhaltsangabeSection I: The Epidemiology of Alcohol Use and Lung Health Chapter 1A Brief History of Alcohol Use and Abuse in Human HistoryDavid M. Guidot, MD, Ashish J. Mehta, MD, MSc Chapter 2Overview of the Evolving Recognition of the Health Effects of Excessive Alcohol Use Over the Past Two Centuries Including the Classic CitationsDavid M. Guidot, MD, Ashish J. Mehta, MD, MSc Chapter 3Current Definitions of Alcohol Use Disorders and the Use of Validated Questionnaires in Clinical Practice and ResearchKaren Drexler, M.D Chapter 4The Epidemiology of Alcohol Abuse and PneumoniaKyle I. Happel, M.D Chapter 5The Epidemiology of Alcohol and Acute Respiratory Distress SyndromeBrendan J. Clark, MD and Ellen L. Burnham, MD, MS Section II: The Pathophysiology of the 'Alcoholic Lung' Chapter 6Alcohol, the Upper Airway, and Mucociliary Dysfunction in the Conducting AirwaysTodd A. Wyatt, PhD and Joseph H. Sisson, MD Chapter 7Alcohol and the Alveolar MacrophageSamantha M. Yeligar, MS, PhD; Yan Liang, PhD; Lou Ann S. Brown, PhD Chapter 8Alcohol and the Alveolar EpitheliumSamuel Molina, Ph.D. and Michael Koval, Ph.D. Chapter 9Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol DepletionSamantha M. Yeligar, MS, PhD; Yan Liang, PhD; and Lou Ann S. Brown, PhD Chapter 10Alcohol and the Adaptive Immune Response in the Airway: Dendritic Cell and Lymphocyte ImpairmentsKevin L. Legge, PhD* and Thomas J. Waldschmidt, PhD Chapter 11Alcohol Impairment of Granulocyte Function During Lung InfectionGregory J. Bagby, Ph.D., Kyle Happel, MD, J Nicholas Melvan, MD, Ph.D Chapter 12:  Disruption in the Dynamic Balance Between Transforming Growth Factor-ß and Granulocyte/Macrophage Colony-stimulating Factor Signaling within the Alveolar Space of the Alcoholic Lung: Impact on Epithelial and Macrophage FunctionDavid M. Guidot, MD, Ashish J. Mehta, MD, MSc Chapter 13Alcohol-mediated Zinc Deficiency within the Alveolar Space: A Potential Fundamental Mechanism Underlying Oxidative Stress and Cellular Dysfunction in the Alcoholic LungAshish J. Mehta, MD, MSc, David M. Guidot, MD Section III: Special Circumstances Chapter 14The Impact of Alcohol Abuse on Multiple Organ Dysfunction in the Surgical PatientKatharina Chalk, MDClaudia Spies, MD Chapter 15Alcohol and HIV: Experimental and Clinical Evidence of Combined Impact on the LungSushma K. Cribbs, MD, David Rimland, MD Chapter 16Maternal Alcohol Use and the Neonate Theresa W. Gauthier, MD, Danielle Giliberti, MD, PhD                        Sowmya S. Mohan, MD, Juna Konomi, BA, Lou Ann S. Brown, PhD