Central Nervous System Diseases and Inflammation

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Bibliografische Daten
ISBN/EAN: 9781441944801
Sprache: Englisch
Umfang: viii, 318 S., 1 s/w Illustr., 9 farbige Illustr.,
Auflage: 1. Auflage 2008
Einband: kartoniertes Buch

Beschreibung

InhaltsangabeMicroglia: A CNS-Specific Tissue Macrophage.- Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments.- Pericytes.- Imaging Microglia in the Central Nervous System: Past, Present and Future.- Cytokines in CNS Inflammation and Disease.- Arachidonic Acid Metabolites: Function in Neurotoxicity and Inflammation in the Central Nervous System.- Pattern Recognition Receptors in CNS Disease.- Central Nervous System Diseases and Inflammation.- Chemokines and Autoimmune Demyelination.- Chemokine Actions in the CNS: Insights from Transgenic Mice.- Chemokines and Spinal Cord Injury.- The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System.- CNS Dendritic Cells in Inflammation and Disease.- MHC Class I Expression and CD8 T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain.

Inhalt

Section I - Microglia and CNS Disease.- 1. Microglia: a CNS-Specific Tissue Macrophage.- Shweta S. Puntambekar, Jonathan M. Doose, Monica J Carson.- 2. Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments.- S. A. Austin and C. K. Combs.- 3. Pericytes.- Martin Krüger and Ingo Bechmann.- 4. Imaging Microglia in the Central Nervous System: Past, Present, and Future.- Dimitrios Davalos and Katerina Akassoglou.- Section II - Innate Immune Responses within the Brain.- 5. Cytokines in CNS inflammation and disease.- Malu G. Tansey and Tony Wyss-Coray.- 6. Arachidonic acid metabolites: Function in neurotoxicity and inflammation in the central nervous system.- and T.J. Montine.- 7. Pattern Recognition Receptors in CNS Disease.- Pamela A. Carpentier, D¿Anne S. Duncan, Stephen D. Miller.- 8. The Complement System in the CNS: Thinking again.- Andrea J. Tenner and Karntipa Pisalyaput.- Section III - Chemokines and CNS Disease.- 9. Chemokines and autoimmune demyelination.- Michaela Fux, Jason Millward, and Trevor Owens.- 10. Chemokine actions in the CNS: Insights from transgenic models.- Marcus Müller and Iain L. Campbell.- 11. Chemokines and Spinal Cord Injury.- Maya N. Hatch and Hans S. Keirstead.- 12. The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System.- Michelle J. Hickey, Linda N. Stiles, Chris S. Schaumburg, and Thomas E. Lane.- Section IV - Antigen Presentation and Immune Responses within the Brain.- 13. CNS Dendritic Cells in Inflammation and Disease.- Samantha L. Bailey and Stephen D. Miller.- 14. MHC class I Expression and CD8+ T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain.- Cornelia Bergmann and Pedro Lowenstein.